Direct-to-Implant Reconstruction with Microthane®

Clinical Evidence and Advantages

Direct-to-Implant (DTI) reconstruction using Microthane® - our polyurethane-covered implant surface - offers key advantages in single-stage breast reconstruction, particularly for prepectoral placement1. The micro-polyurethane 3D Matrix supports fibroblast ingrowth and tissue adherence, enhancing implant stability and reducing seroma, malposition, and capsular contracture risk3,5.

Microthane® implants are a good choice even in cases of radiation treatment, which is known to dramatically increase the risk of capsular contracture3. With capsular contracture rates that can go up to 50% with smooth implants, the capsular contracture rate for micro-polyurethane foam covered implants is as low as 0-3%.4,5

 

Microthane® significantly reduces the risks commonly associated with breast reconstruction - particularly in challenging cases like postmastectomy radiation therapy (PMRT)

Loreti et al. reported a 70% lower risk of severe capsular contracture (grade III & IV) in PMRT patients receiving polyurethane implants compared to textured ones 3.
Additionally, De Vita et al. reported 93% patient satisfaction in a large cohort undergoing prepectoral DTI with Microthane®, highlighting its long-term comfort and aesthetic reliability 6.

These benefits support the cost-effectiveness of Microthane® versus acellular dermal matrices (ADM) due to reduced complications and fewer reoperations. 

 

 

B-Lite® Microthane® – an additional advantage

The need for a large size implant to fill the tissue envelope can be a challenge in breast reconstruction. Thin skin with poor tissue quality to achieve projection on the lower pole may be a demanding challenge.

B-Lite® lightweight implants covered with Microthane® are designed to be stable and predictable. They weigh up to 30% less than traditional silicone implants while maintaining an equivalent size, form, and function. Lightweight implant applies similar pressure as a conventional implant of about half the volume7 and support tissue stability.8

Great adherence and less stress are two factors that allow you to have better control over implant stability and implant long-term surgical outcome. Regular users around the world confirm that they and their patients are post-operatively satisfied and confident.9

“I believe B-Lite® in combination with Microthane® is the best implant a patient can get for reconstruction. The less pressure that B-Lite® delivers plus the stability and control of Microthane® gives patients an unbelievable advantage.”

Prof. Roy de Vita, Chief of Plastic and Reconstructive Surgery Dept. Regina Elena National Cancer Institute, Rome

 

2025

Lisa A, et al.

Outcomes, indications and predictive factors for complications in postmastectomy prepectoral reconstructions with polyurethane foam-coated implants

The Breast, Vol. 83, 104520
DOI: 10.1016/j.breast.2025.104520

2025

Salgarello M, et al.

Immediate Breast Reconstruction with Prepectoral Polyurethane‑Covered Implant After Conservative Mastectomy in Large and Ptotic Breasts

Aesthetic Plastic Surgery
DOI: 10.1007/s00266-025-05070-w

2024

Catanuto G, et al.

One‑Stage Implant‑Based Breast Reconstruction With Polyurethane‑Coated Device: Standardized Assessment of Outcomes

Aesthetic Surgery Journal
DOI: 10.1093/asj/sjad330

2024

Lembo F, et al.

Immediate Breast Reconstruction in Skin‑Reducing Mastectomy with Prepectoral Polyurethane Implant Covered with an Autologous Dermo‑Adipose Flap

Aesthetic Plastic Surgery
DOI: 10.1007/s00266-024-04900-x

2024

Correia‑Pinto JM, et al.

Impact of polyurethane versus acellular dermal matrix coating on prepectoral reconstruction outcomes: Interface does matter

JPRAS
DOI: 10.1016/j.bjps.2024.01.029

2022

Urban C, et al.

Prepectoral Direct‑to‑Implant Breast Reconstruction without Placement of Acellular Dermal Matrix or Mesh after Nipple‑Sparing Mastectomy

Plastic and Reconstructive Surgery
DOI: 10.1097/PRS.0000000000008940

2022

De Vita R, et al.

Extended Clinical Experience With Nipple‑Sparing Mastectomy and Prepectoral Polyurethane Implant Positioning (BRAND4P)

Clinical Breast Cancer
DOI: 10.1016/j.clbc.2021.11.009

2021

Coyette M, et al.

Prepectoral immediate breast reconstruction with polyurethane foam‑coated implants: Feasibility and early results in risk‑reducing and therapeutic mastectomies

JPRAS
DOI: 10.1016/j.bjps.2021.06.050

2021

Salgarello M, et al.

Direct to Implant Breast Reconstruction With Prepectoral Micropolyurethane Foam‑Coated Implant: Analysis of Patient Satisfaction

Clinical Breast Cancer
DOI: 10.1016/j.clbc.2020.10.009

Sources:

1. Salgarello M, et al. (2025). Immediate Breast Reconstruction with Prepectoral Polyurethane-Covered Implant After Conservative Mastectomy in Large and Ptotic Breasts. Aesthetic Plastic Surgery.
3. Loreti A, et al. (2020). Lower incidence of capsular contracture with polyurethane-covered implants post-radiation therapy. The Breast, 50:1–7. DOI: 10.1016/j.breast.2020.01.008
4. Pompei S, Evangelidou D, Arelli F, Ferrante G. (2016). The Modern Polyurethane-Coated Implant in Breast Augmentation: Long-Term Clinical Experience. Aesthetic Surgery Journal, 36(10):1124–1129. DOI: 10.1093/asj/sjw183
5. Handel N, Cordray T, Gutierrez J, Jensen JA. (2006). A long-term study of outcomes, complications, and patient satisfaction with breast implants. Plast Reconstr Surg. 117(3):757–67. DOI: 10.1097/01.prs.0000201457.00772.1d
6. De Vita R, et al. (2022). Extended Clinical Experience With Nipple-Sparing Mastectomy and Prepectoral Polyurethane Implant Positioning (BRAND4P method). Clinical Breast Cancer, 22(5): e623–e628. DOI: 10.1016/j.clbc.2022.03.005
7. Breast Implants and Pressure (2018), G&G, Data on File.
8. Vegas MR, Martin del Yerro JL, et al. (2013). Understanding implant-soft tissue dynamics in the augmented breast. Aesthetic Plast Surg, 37(5): 922–930. DOI: 10.1007/s00266-013-0197-y
9. Excellent and very good patient satisfaction Survey of 296 B-Lite® patients (2017); G&G, Data on File.